ABSTRACT
Objective:To observe the clinical effect of Shufeng Jiedu capsules combined with the conventional treatment on upper airway cough syndrome(UACS). Methods:Totally 55 patients with UACS and basic nasal or sinus diseases were randomly divided into two groups:the treatment group (n = 28) and the control group (n = 27). The treatment group was treated with Shufeng Jiedu capsules combined with the regimen for the control group,40 mg·kg-1,3 times a day, and the regimen for the control group was as follows:loratadine tablets, 10 mg,qd, budesonide nasal spray hormone 128 μg, bid, roxithromycin dispersible tablets,0.15 g,qd. The treatment course was 4 weeks. The changes of symptom scores were observed and the adverse reactions were recorded to compare the efficacy between the groups. Results:The total effective rate of the treatment group was 85.71%, which was significantly higher than that of the control group(75.37%,P <0.05). The cough and nasal symptoms were notably improved in the two groups after the treatment(P < 0.05),and all the symptom scores in the treatment group were better than those in the control group (P < 0.05). Conclusion:Shufeng Jiedu capsules combined with the conventional treatment can improve the efficacy in the treatment of UACS.